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PLLA(Poly-L-lactic acid) + H-HA + L-HA

Safety, Effectiveness, Convenience

What is PLLA?

PLLA(Poly-L-lactic acid) is a biocompatible, biodegradable, immunologically inert synthetic polymer that stimulates collagen synthesis,
leading to gradual volume reestablishment.
As the PLLA microparticles degrade, the inflammatory reaction responsible for the degradation of the particles promotes the forma-tion
of fibrous connective tissue and neocollagenesis, leading to gradual volume replacement. In addition,
PLLA increases fibroblast activity and stimulates collagen synthesis.

What is H-HA+L-HA?

Hyaluronic acid (HA) is dermal agent for the correction of age-related soft tissue defects, such as skin laxity, loss of hydration, wrinkle
formation and roughening of skin texture.
H-HA(high-molecular-weight hyaluronic acid) and L-HA(low-molecular-weight hyaluronic acid) is injectable formulation of cooperative
hybrid HA complexes.
SYNERFILL is the specially compounded PLLA+H-HA+L-HA collagen stimulating and lifting filler that stimulates collagen inside of skin to
induce collagenesis and improves wrinkles and restore facial volume losses.
Also helps reduction of wrinkle depth, smoothing of skin texture and improves skin hydration, skin compli-ance & skin elasticity.

SEM picture of SYNERFILL PLLA

SYNERFILL has a spherical shape with internal pores, so when collagen is synthesized, a larger amount of collagen is produced and its duration is longer.
Due to the nature of PLLA, its duration is longer at 2 years compared to other companies’ PLLA and PDLLA.
When injecting subcutaneous fat layer, pain is minimized by using a thin needle.

SEM Picture of other company

Strong point of SYNERFILL

Company G*** V*** HEALINK
Product S**** J**** SYNERFILL Face SYNERFILL Body
Meterial PLLA
CMC
Mannitol
PDLLA
HA
PLLA
H-HA
L-HA
PLLA
H-HA
L-HA
Powder Shape Broken stone shape Broken stone shape Microporous Sphere Microporous Sphere
Volume 368mg
PLLA - 150mg
CMC - 90mg
Mannitol - 128mg
368mg
PLLA - 150mg
CMC - 90mg
Mannitol - 128mg
260mg
PLLA-200mg
H-HA - 30mg
L-HA - 30mg
520mg
PLLA=400mg
H-HA - 60mg
L-HA - 60mg
Collagen production rate High Medium High High
Persistence 24 month 6 ~ 12 month 24 month 24 month
Immediate impact No Yes Yes Yes
Elastin production No Midium High High

Advanced Bio Stimulator

Ingredients
  • - PLLA (Poly-L-lactic acid): Face (200mg) / Body (400mg)
  • - H-HA: Face (30mg) / Body (60mg)
  • - L-HA: Face (30mg) / Body (60mg)
Indication
  • - Stimulation and generation of collagen under the skin
  • - Reducing fine wrinkles
  • - Smoothing of skin texture
  • - Smoothing of skin texture
  • - Improves skin hydration, skin compliance, skin elasticity
  • - Volume replenishment
Treatment Area
  • - Nasolabial folds, Temple, Cheek, Jowls, Eye, Chin, Jawline, Marionette lines, Forehead, Neck, Breast, Vagina, Penis Shaft, Back of Hand
Why SYNERFILL?
  • - Long lasting
  • - Evenly restores volume & improves deep wrinkles
  • - Quick procedure and effect
  • - No residues left in the body
  • - FDA Proven Safety
Treatment
  • - 2~3 treatments / 1 month interval
Duration
  • - 24 months.
Volume
  • - Face(260 mg) / vial / box
  • - Body(520 mg) / vial / box

Advanced Bio Stimulator

Ingredients
  • - PLLA (Poly-L-lactic acid): Face (200mg) / Body (400mg)
  • - H-HA: Face (30mg) / Body (60mg)
  • - L-HA: 60mg
Indication
  • - Stimulation and generation of collagen under the skin
  • - Reducing fine wrinkles
  • - Smoothing of skin texture
  • - Smoothing of skin texture
  • - Improves skin hydration, skin compliance, skin elasticity
  • - Volume replenishment
Treatment Area
  • - Nasolabial folds, Temple, Cheek, Jowls, Eye, Chin, Jawline, Marionette lines, Forehead, Neck, Breast, Vagina, Penis Shaft, Back of Hand
Why SYNERFILL?
  • - Long lasting
  • - Evenly restores volume & improves deep wrinkles
  • - Quick procedure and effect
  • - No residues left in the body
  • - FDA Proven Safety
Treatment
  • - 2~3 treatments / 1 month interval
Duration
  • - 24 months.
Volume
  • - Face(260 mg) / vial / box
  • - Body(520 mg) / vial / box

Before and after

Synerfill Face
(PLLA+H-HA+L-HA) Description

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Synerfill Face,
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Synerfill Body
(PLLA+H-HA+L-HA) Description

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Synerfill Body,
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Synerfill Face
Treatment Protocol

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Synerfill Body
Treatment Protocol

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Treatment example

Media